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Readers Share Thoughts: Kathy responded with this observation: A high B12 reading could indicate a methylation issue which causes the B12 to pool in ones system because it can not be broken down and used properly

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Speak to your GP if you experience: Severe or persistent abdominal pain, particularly in the upper right or upper middle abdomen Jaundice (yellowing of the skin or whites of the eyes) Persistent vomiting Dark urine or pale stools Fever alongside abdominal symptoms Persistent watery or urgent diarrhoea that doesnt settle after the first few weeks on a stable Mounjaro dose Heartburn or reflux is noticeably worse than before starting Mounjaro Some people experience increased bile reflux after gallbladder removal, and Mounjaros slowing of gastric emptying can make this worse

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